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Issue 16, 2014
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Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

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Abstract

Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent thermometry. We demonstrate how Er:Yb:NaY2F5O nanocrystals present a higher thermal sensitivity than the Er:Yb:NaYF4 ones and that their lifetime thermal coefficient is comparable to those corresponding to other nano-sized luminescent systems already used for high resolution lifetime fluorescence thermal sensing. We evaluate the potential use of Er:Yb:NaY2F5O nanoparticles as lifetime based thermal probes by providing the first experimental evidence on sub-tissue lifetime fluorescence thermal sensing by using up-conversion nanoparticles in an ex vivo experiment.

Graphical abstract: Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

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Publication details

The article was received on 29 Apr 2014, accepted on 09 Jun 2014 and first published on 11 Jun 2014


Article type: Paper
DOI: 10.1039/C4NR02305F
Citation: Nanoscale, 2014,6, 9727-9733
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    Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

    Ol. A. Savchuk, P. Haro-González, J. J. Carvajal, D. Jaque, J. Massons, M. Aguiló and F. Díaz, Nanoscale, 2014, 6, 9727
    DOI: 10.1039/C4NR02305F

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