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Issue 9, 2014
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Natural products containing ‘decalin’ motif in microorganisms

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Abstract

Covering: up to February 2014

Microorganisms are well-known producers of a wide variety of bioactive compounds that are utilized not only for their primary metabolism but also for other purposes such as defense, detoxification, or communication with other micro- and macro-organisms. Natural products containing a ‘decalin ring’ occur often in microorganisms. They exhibit diverse and remarkable biological activities, including antifungal, antibacterial, anticancer and immunosuppressive activities, to name a few. This review surveys the natural decalin-type compounds that have been isolated from microorganisms, with emphasis on both chemical and biological implications. Total syntheses of some important decalin moiety-containing natural products are also highlighted.

Graphical abstract: Natural products containing ‘decalin’ motif in microorganisms

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Article information


Submitted
19 Mar 2014
First published
02 Jul 2014

This article is Open Access

Nat. Prod. Rep., 2014,31, 1175-1201
Article type
Review Article

Natural products containing ‘decalin’ motif in microorganisms

G. Li, S. Kusari and M. Spiteller, Nat. Prod. Rep., 2014, 31, 1175
DOI: 10.1039/C4NP00031E

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    [Original citation] - Published by The Royal Society of Chemistry.

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