Issue 2, 2014

A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides

Abstract

Covering: 2009–2013

This Highlight describes the recently discovered prodrug activation mechanism found in the biosynthesis of nonribosomally produced peptides and peptide/polyketide hybrids as well as related mechanisms.

Graphical abstract: A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides

Article information

Article type
Highlight
Submitted
29 Aug 2013
First published
20 Dec 2013

Nat. Prod. Rep., 2014,31, 154-159

Author version available

A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides

D. Reimer and H. B. Bode, Nat. Prod. Rep., 2014, 31, 154 DOI: 10.1039/C3NP70081J

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