Issue 8, 2014
From the journal:

New Journal of Chemistry

A specific and rapid “on-off” acenaphthenequinone-based probe for HOCl detection and imaging in living cells†

Jie Zhao,a   Hongjuan Li,a   Kui Yang,a   Shiguo Sun,*a   Aiping Lu*b  and  Yongqian Xu*a  

* Corresponding authors

a College of Science, Northwest A&F University, Yangling, Shaanxi, China
E-mail: xuyq@nwsuaf.edu.cn, sunsg@nwsuaf.edu.cn

b Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Dongzhimen, Beijing 100700, China
E-mail: lap64067611@126.com

Abstract

A fluorescent probe exhibiting specific and sensitive properties towards HOCl was successfully developed on the basis of the Baeyer–Villiger reaction. It worked well both in solution and on test papers, allowing the facile monitoring of hypochlorite. The probe was further used for imaging in living cells.

Graphical abstract: A specific and rapid “on-off” acenaphthenequinone-based probe for HOCl detection and imaging in living cells

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Article information

DOI
https://doi.org/10.1039/C4NJ00470A
Article type
Letter
Submitted
28 Mar 2014
Accepted
20 May 2014
First published
22 May 2014

New J. Chem., 2014,38, 3371-3374

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A specific and rapid “on-off” acenaphthenequinone-based probe for HOCl detection and imaging in living cells

J. Zhao, H. Li, K. Yang, S. Sun, A. Lu and Y. Xu, New J. Chem., 2014, 38, 3371 DOI: 10.1039/C4NJ00470A

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