Issue 4, 2014
From the journal:

New Journal of Chemistry

In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

Alexandre Aillerie,ab   Sylvain Pellegrini,ab   Till Bousquet*ab  and  Lydie Pélinski*ab  

* Corresponding authors

a Université Lille Nord de France, F-59000 Lille, France
E-mail: till.bousquet@univ-lille1.fr, lydie.pelinski@univ-lille1.fr

b Université de Lille 1, Unité de Catalyse et de Chimie du Solide, UMR CNRS 8181, ENSCL, B.P. 108, 59652 Villeneuve d'Ascq, France

Abstract

The synthesis of primary aminoquinolines from iodoquinolines was carried out in the presence of copper(I) iodide and formamide as the solvent and source of ammonia generated in situ. The reaction proceeded under mild conditions within a few hours and was applicable to various iodoquinolines.

Graphical abstract: In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

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Article information

DOI
https://doi.org/10.1039/C4NJ00046C
Article type
Letter
Submitted
09 Jan 2014
Accepted
10 Feb 2014
First published
03 Mar 2014

New J. Chem., 2014,38, 1389-1391

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In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

A. Aillerie, S. Pellegrini, T. Bousquet and L. Pélinski, New J. Chem., 2014, 38, 1389 DOI: 10.1039/C4NJ00046C

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