Issue 2, 2014

A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners

Abstract

We developed a simple, rapid and efficient microwave irradiation-assisted protocol that is 1- to 2-orders of magnitude faster than conventional techniques, providing an expedient access to the sialic acid congeners Neu5Ac1Me (1), Neu5Acβ1,2Me2 (2), Neu5Ac1Me O-peracetate (3) and 4,5-oxazoline of Neu5Ac2en1Me O-peracetate (4).

Graphical abstract: A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners

Supplementary files

Article information

Article type
Letter
Submitted
03 Dec 2013
Accepted
06 Dec 2013
First published
09 Dec 2013

New J. Chem., 2014,38, 507-510

Author version available

A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners

J. P. Saludes, D. Sahoo and I. A. Monreal, New J. Chem., 2014, 38, 507 DOI: 10.1039/C3NJ01459B

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