Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 7, 2014
Previous Article Next Article

Multiple impacts of zinc on immune function

Author affiliations

Abstract

Even though zinc is essential for virtually all processes in the human body, observations during zinc deficiency indicate that the absence of this trace element most severely affects the immune response. Numerous investigations of the cellular and molecular requirements for zinc in the immune system have indicated that there is not just one single function of zinc underlying this essentiality. In fact, there is a wide range of different roles of zinc in immunity. This review summarizes the recent developments in three of the major fields: the role of zinc as a second messenger in signal transduction, the importance of zinc for immune cell function, and the competition for zinc between the host and the pathogen, a concept known as nutritional immunity.

Graphical abstract: Multiple impacts of zinc on immune function

Back to tab navigation

Article information


Submitted
27 Nov 2013
Accepted
05 Feb 2014
First published
05 Feb 2014

Metallomics, 2014,6, 1175-1180
Article type
Minireview

Multiple impacts of zinc on immune function

H. Haase and L. Rink, Metallomics, 2014, 6, 1175
DOI: 10.1039/C3MT00353A

Social activity

Search articles by author

Spotlight

Advertisements