Issue 3, 2014
From the journal:

Molecular BioSystems

Gene expression scaled by distance to the genome replication site†

Bei-Wen Ying,ab   Saburo Tsuru,b   Shigeto Seno,b   Hideo Matsudab  and  Tetsuya Yomo*bcd  

* Corresponding authors

a Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan

b Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan
E-mail: yomo@ist.osaka-u.ac.jp
Fax: +81 6 6879 7433
Tel: +81 6 6879 4171

c Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan

d Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST), Suita, Osaka 565-0871, Japan

Abstract

A simple mode of gene expression scaled by the distance from the chromosomal location of the gene to the genome replication site oriC was determined. The common formula representing the effect of genomic position on expression capacity not only supports the multifork replication model but also provides a base correlation for theoretical simulation and synthetic constructs.

Graphical abstract: Gene expression scaled by distance to the genome replication site

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Article information

DOI
https://doi.org/10.1039/C3MB70254E
Article type
Communication
Submitted
28 Jun 2013
Accepted
22 Nov 2013
First published
25 Nov 2013

Mol. BioSyst., 2014,10, 375-379

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Gene expression scaled by distance to the genome replication site

B. Ying, S. Tsuru, S. Seno, H. Matsuda and T. Yomo, Mol. BioSyst., 2014, 10, 375 DOI: 10.1039/C3MB70254E

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