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Issue 4, 2014
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Live human nasal epithelial cells (hNECs) on chip for in vitro testing of gaseous formaldehyde toxicity via airway delivery

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Abstract

Cell models based on human nasal epithelial stem/progenitor cells (hNESPCs) are developed to obtain functional ciliated cells on modified Transwell inserts. The live hNECs are integrated into microfluidic platforms to mimic the 3D features of the human upper airway for in vitro testing of gaseous formaldehyde toxicity via airway delivery.

Graphical abstract: Live human nasal epithelial cells (hNECs) on chip for in vitro testing of gaseous formaldehyde toxicity via airway delivery

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Article information


Submitted
25 Oct 2013
Accepted
28 Nov 2013
First published
28 Nov 2013

Lab Chip, 2014,14, 677-680
Article type
Communication
Author version available

Live human nasal epithelial cells (hNECs) on chip for in vitro testing of gaseous formaldehyde toxicity via airway delivery

W. Wang, Y. Yan, C. W. Li, H. M. Xia, S. S. Chao, D. Y. Wang and Z. P. Wang, Lab Chip, 2014, 14, 677
DOI: 10.1039/C3LC51208H

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