Issue 20, 2014

A highly flexible and compact magnetoresistive analytic device


A grand vision of realization of smart and compact multifunctional microfluidic devices for wearable health monitoring, environment sensing and point-of-care tests emerged with the fast development of flexible electronics. As a vital component towards this vision, magnetic functionality in flexible fluidics is still missing although demanded by the broad utility of magnetic nanoparticles in medicine and biology. Here, we demonstrate the first flexible microfluidic analytic device with integrated high-performance giant magnetoresistive (GMR) sensors. This device can be bent to a radius of 2 mm while still retaining its full performance. Various dimensions of magnetic emulsion droplets can be probed with high precision using a limit of detection of 0.5 pl, providing broad applicability in high-throughput droplet screening, flow cytometry and drug development. The flexible feature of this analytic device holds great promise in the realization of wearable, implantable multifunctional platforms for biomedical, pharmaceutical and chemical applications.

Graphical abstract: A highly flexible and compact magnetoresistive analytic device

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Article information

Article type
26 Jun 2014
07 Aug 2014
First published
27 Aug 2014
This article is Open Access
Creative Commons BY license

Lab Chip, 2014,14, 4050-4058

Author version available

A highly flexible and compact magnetoresistive analytic device

G. Lin, D. Makarov, M. Melzer, W. Si, C. Yan and O. G. Schmidt, Lab Chip, 2014, 14, 4050 DOI: 10.1039/C4LC00751D

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