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Issue 6, 2014
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Dynamically reconfigurable fibre optical spanner

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Abstract

In this paper we describe a pneumatically actuated fibre-optic spanner integrated into a microfluidic Lab-on-a-Chip device for the controlled trapping and rotation of living cells. The dynamic nature of the system allows interactive control over the rotation speed with the same optical power. The use of a multi-layer device makes it possible to rotate a cell both in the imaging plane and also in a perpendicular plane allowing tomographic imaging of the trapped living cell. The integrated device allows easy operation and by combining it with high-resolution confocal microscopy we show for the first time that the pattern of rotation can give information regarding the sub-cellular composition of a rotated cell.

Graphical abstract: Dynamically reconfigurable fibre optical spanner

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Publication details

The article was received on 14 Nov 2013, accepted on 20 Jan 2014 and first published on 20 Jan 2014


Article type: Paper
DOI: 10.1039/C3LC51277K
Citation: Lab Chip, 2014,14, 1186-1190
  • Open access: Creative Commons BY-NC license
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    Dynamically reconfigurable fibre optical spanner

    T. Kolb, S. Albert, M. Haug and G. Whyte, Lab Chip, 2014, 14, 1186
    DOI: 10.1039/C3LC51277K

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