Issue 39, 2014
From the journal:

Dalton Transactions

Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity†

Suman Kumar Tripathy,a   Umasankar De,b   Niranjan Dehury,a   Satyanarayan Pal,c   Hyung Sik Kim*b  and  Srikanta Patra*a  

* Corresponding authors

a School of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar-751007, India
E-mail: srikanta@iitbbs.ac.in
Tel: +91-674 2576053

b Division of Toxicology, School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea
E-mail: hkims@skku.edu
Tel: +82-31-290-7789

c Department of Chemistry, Ravenshaw University, Cuttack 753 003, Orissa, India

Abstract

Phpy bridged homodinuclear Ru–Ru (1) and heterodinuclear Ir–Ru complexes (2) have been developed. Complex 2 induces autophagy towards the cisplatin resistant human breast cancer (MCF7) cell line, whereas 1 is inactive.

Graphical abstract: Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity

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Article information

DOI
https://doi.org/10.1039/C4DT01033G
Article type
Communication
Submitted
07 Apr 2014
Accepted
13 Aug 2014
First published
14 Aug 2014

Dalton Trans., 2014,43, 14546-14549

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Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity

S. K. Tripathy, U. De, N. Dehury, S. Pal, H. S. Kim and S. Patra, Dalton Trans., 2014, 43, 14546 DOI: 10.1039/C4DT01033G

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