Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 29, 2014
Previous Article Next Article

Selectivity in fragmentation of N-methylacetamide after resonant K-shell excitation

Author affiliations

Abstract

The fragmentation pattern of the peptide model system, N-methylacetamide, is investigated using ion time-of-flight (TOF) spectroscopy after resonant K-shell excitation. Corresponding near-edge X-ray absorption fine structure (NEXAFS) spectra recorded at high resolution at the C1s, N1s and O1s edges are presented. Analysis of the ion TOF data reveals a multitude of fragmentation channels and dissociation pathways. Comparison between the excitation of six different resonances in the vicinity of the C1s, N1s and O1s edges suggests evidence for site-selective bond breaking. In particular the breaking of the peptide bond and the N–Cα bond show a clear correlation with resonant excitation at the N1s edge. Also, stronger tendencies towards site-selective bond breaking are found for the generation of single ions compared with ion pairs. Analysis of angular distributions of ions from breakage of the peptide bond yields a fragmentation time of <400 fs.

Graphical abstract: Selectivity in fragmentation of N-methylacetamide after resonant K-shell excitation

Back to tab navigation

Publication details

The article was received on 12 Mar 2014, accepted on 14 May 2014 and first published on 18 Jun 2014


Article type: Paper
DOI: 10.1039/C4CP01067A
Citation: Phys. Chem. Chem. Phys., 2014,16, 15231-15240

  •   Request permissions

    Selectivity in fragmentation of N-methylacetamide after resonant K-shell excitation

    P. Salén, M. Kamińska, R. J. Squibb, R. Richter, M. Alagia, S. Stranges, P. van der Meulen, J. H. D. Eland, R. Feifel and V. Zhaunerchyk, Phys. Chem. Chem. Phys., 2014, 16, 15231
    DOI: 10.1039/C4CP01067A

Search articles by author

Spotlight

Advertisements