Chirality effects on proline-substituted serine octamers revealed by infrared photodissociation spectroscopy

Abstract

Chiral preferences exist in proline-substituted serine octamers. For ions of [L-Ser₆ + Pro₂]H⁺, the stability preference is [L-Ser₆ + L-Pro₂]H⁺ > [L-Ser₆ + D-Pro₂]H⁺ > [L-Ser₆ + L-Pro₁ + D-Pro₁]H⁺. Infrared photodissociation (IRPD) experiments were performed for the observed proline-substituted octamer ions in the range from 2700 to 3750 cm⁻¹. Chiral differentiation was achieved using the IRPD method, and the progressive changes in IRPD spectra due to the substitution were also reflected.