Carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging

Liu He; Tingting Wang; Jiping An; Xiaomeng Li; Lingyu Zhang; Lu Li; Guangzhe Li; Xiaotong Wu; Zhongmin Su; Chungang Wang

doi:10.1039/C3CE42506A

Carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging†

Liu He,^a Tingting Wang,^b Jiping An,^c Xiaomeng Li,*^a Lingyu Zhang,^a Lu Li,^a Guangzhe Li,^a Xiaotong Wu,^a Zhongmin Su^a and Chungang Wang*^a

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* Corresponding authors

^a Faculty of Chemistry, Northeast Normal University, Changchun 130024, PR China
E-mail: wangcg925@nenu.edu.cn, lixm441@nenu.edu.cn

^b School of Chemistry & Environmental Engineering, Changchun University of Science and Technology, Changchun, PR China

^c Hospital of Stomatology, Jilin University, Changchun 130021, PR China

Abstract

A facile two-step method was developed to fabricate green fluorescent carbon nanodots@zeolitic imidazolate framework-8 nanoparticles (C-dots@ZIF-8 NPs) with tunable size and fluorescence intensity, which acted as platforms for simultaneous pH-responsive drug delivery and fluorescence imaging of cancer cells.

CrystEngComm

Carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging†

Abstract

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Carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging

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