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Issue 82, 2014
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Aptamer-based cell imaging reagents capable of fluorescence switching

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Abstract

We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

Graphical abstract: Aptamer-based cell imaging reagents capable of fluorescence switching

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Supplementary files

Article information


Submitted
21 May 2014
Accepted
21 Aug 2014
First published
22 Aug 2014

Chem. Commun., 2014,50, 12329-12332
Article type
Communication

Aptamer-based cell imaging reagents capable of fluorescence switching

Y. K. Jung, M. Woo, H. T. Soh and H. G. Park, Chem. Commun., 2014, 50, 12329
DOI: 10.1039/C4CC03888F

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