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Issue 14, 2014
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Five-plex isotope dimethyl labeling for quantitative proteomics

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Abstract

Stable isotope dimethyl labeling, a widely used method for quantitative proteomics, was extended to five channels for the first time. Comprehensive proteome and phosphoproteome quantification validated the high quantification accuracy and throughput of this five-plex method.

Graphical abstract: Five-plex isotope dimethyl labeling for quantitative proteomics

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Supplementary files

Article information


Submitted
17 Oct 2013
Accepted
06 Dec 2013
First published
09 Dec 2013

Chem. Commun., 2014,50, 1708-1710
Article type
Communication

Five-plex isotope dimethyl labeling for quantitative proteomics

Y. Wu, F. Wang, Z. Liu, H. Qin, C. Song, J. Huang, Y. Bian, X. Wei, J. Dong and H. Zou, Chem. Commun., 2014, 50, 1708
DOI: 10.1039/C3CC47998F

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