Issue 92, 2014
From the journal:

Chemical Communications

A universal molecular translator for non-nucleic acid targets that enables dynamic DNA assemblies and logic operations†

Wei Tang,a   Shichao Hu,a   Huaming Wang,a   Yan Zhao,a   Na Lia  and  Feng Liu*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
E-mail: liufeng@pku.edu.cn

Abstract

A universal molecular translator based on the target-triggered DNA strand displacement was developed, which was able to convert various kinds of non-nucleic acid targets into a unique output DNA. This translation strategy was successfully applied in directing dynamic DNA assemblies and in realizing three-input logic gate operations.

Graphical abstract: A universal molecular translator for non-nucleic acid targets that enables dynamic DNA assemblies and logic operations

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Article information

DOI
https://doi.org/10.1039/C4CC07041K
Article type
Communication
Submitted
06 Sep 2014
Accepted
23 Sep 2014
First published
23 Sep 2014

Chem. Commun., 2014,50, 14352-14355

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A universal molecular translator for non-nucleic acid targets that enables dynamic DNA assemblies and logic operations

W. Tang, S. Hu, H. Wang, Y. Zhao, N. Li and F. Liu, Chem. Commun., 2014, 50, 14352 DOI: 10.1039/C4CC07041K

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