Issue 96, 2014
From the journal:

Chemical Communications

Organic nanoparticles with aggregation-induced emission for tracking bone marrow stromal cells in the rat ischemic stroke model†

Kai Li,‡a   Mie Yamamoto,‡bc   Su Jing Chan,b   Mun Yee Chiam,c   Wei Qin,d   Peter Tsun Hon Wong,*b   Evelyn King Fai Yim,*cef   Ben Zhong Tangdg  and  Bin Liu*ah  

* Corresponding authors

a Institute of Materials Research and Engineering, A*STAR, 3 Research Link, Singapore 117602

b Department of Pharmacology, Center for Translational Medicine, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 117597
E-mail: peter_wong@nuhs.edu.sg

c Department of Biomedical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117575
E-mail: eyim@nus.edu.sg

d Department of Chemistry, Division of Biomedical Engineering, Institute for Advanced Study, State Key Laboratory of Molecular Neuroscience, and Institute of Molecular Functional Materials, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China

e Mechanobiology Institute Singapore, National University of Singapore, 5A Engineering Drive 1, Singapore 117411

f Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, IE Kent Ridge Road, Singapore 119228

g SCUT-HKUST Joint Research Laboratory, Guangdong Innovative Research Team, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China

h Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585
E-mail: cheliub@nus.edu.sg
Fax: +65-67791936
Tel: +65-65168049

Abstract

Organic nanoparticles (NPs) with aggregation-induced emission (AIE) have been successfully used for tracking bone marrow stromal cells (BMSCs) in rats with ischemic stroke, highlighting the great potential of such fluorescent NPs in understanding the fate of transplanted stem cells for cell-based therapies.

Graphical abstract: Organic nanoparticles with aggregation-induced emission for tracking bone marrow stromal cells in the rat ischemic stroke model

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC06921H
Article type
Communication
Submitted
02 Sep 2014
Accepted
16 Sep 2014
First published
17 Sep 2014

Chem. Commun., 2014,50, 15136-15139

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Organic nanoparticles with aggregation-induced emission for tracking bone marrow stromal cells in the rat ischemic stroke model

K. Li, M. Yamamoto, S. J. Chan, M. Y. Chiam, W. Qin, P. T. H. Wong, E. K. F. Yim, B. Z. Tang and B. Liu, Chem. Commun., 2014, 50, 15136 DOI: 10.1039/C4CC06921H

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