Issue 82, 2014

Detection of multiple mutations in a single codon of genomic DNA

Abstract

The controller DNA technology allows the detection of multiple mutations in a single codon of genomic DNA. In this technology, the controller DNA is used to control the hybridization of target DNAs with the immobilized DNAs. The controller DNA technology is rapid, specific, and cost-effective for the following reasons, (i) final results in 40 min after PCR, (ii) detection and discrimination of the six mutations in a single codon, and (iii) high sensitivity.

Graphical abstract: Detection of multiple mutations in a single codon of genomic DNA

Supplementary files

Article information

Article type
Communication
Submitted
08 Aug 2014
Accepted
26 Aug 2014
First published
26 Aug 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 12344-12347

Author version available

Detection of multiple mutations in a single codon of genomic DNA

D. R. Sayyed, S. B. Nimse, K. Song and T. Kim, Chem. Commun., 2014, 50, 12344 DOI: 10.1039/C4CC06220E

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