Issue 95, 2014

Rhodium(iii)-catalysed aerobic synthesis of highly functionalized indoles from N-arylurea under mild conditions through C–H activation

Abstract

A Rh(III) catalysed amino arylation of alkynes using copper as the terminal oxidant for regeneration of the catalytically active species under aerobic conditions is described. This novel C–H activation reaction was applied to the synthesis of a wide range of substituted indoles from N-arylureas.

Graphical abstract: Rhodium(iii)-catalysed aerobic synthesis of highly functionalized indoles from N-arylurea under mild conditions through C–H activation

Supplementary files

Article information

Article type
Communication
Submitted
01 Aug 2014
Accepted
27 Sep 2014
First published
06 Oct 2014

Chem. Commun., 2014,50, 14964-14967

Author version available

Rhodium(III)-catalysed aerobic synthesis of highly functionalized indoles from N-arylurea under mild conditions through C–H activation

S. Kathiravan and I. A. Nicholls, Chem. Commun., 2014, 50, 14964 DOI: 10.1039/C4CC06020B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements