Issue 91, 2014
From the journal:

Chemical Communications

A ratiometric fluorescent probe for sensing HOCl based on a coumarin–rhodamine dyad†

Yan-Ru Zhang,a   Xin-Peng Chen,b   Jing-Shao,a   Jia-Yi Zhang,a   Qiong Yuan,a   Jun-Ying Miao*b  and  Bao-Xiang Zhao*a  

* Corresponding authors

a Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China
E-mail: bxzhao@sdu.edu.cn
Fax: +86 531 88564464
Tel: +86 531 88366425

b Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, P. R. China
E-mail: miaojy@sdu.edu.cn

Abstract

We developed a ratiometric fluorescent probe for sensing HOCl based on coumarin and rhodamine acid that is directly used as a detection moiety. The probe shows high selectivity and sensitivity toward HOCl under best working conditions of myeloperoxidase by which HOCl can be generated from hydrogen peroxide and chloride.

Graphical abstract: A ratiometric fluorescent probe for sensing HOCl based on a coumarin–rhodamine dyad

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Article information

DOI
https://doi.org/10.1039/C4CC05976J
Article type
Communication
Submitted
31 Jul 2014
Accepted
25 Sep 2014
First published
25 Sep 2014

Chem. Commun., 2014,50, 14241-14244

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A ratiometric fluorescent probe for sensing HOCl based on a coumarin–rhodamine dyad

Y. Zhang, X. Chen, Jing-Shao, J. Zhang, Q. Yuan, J. Miao and B. Zhao, Chem. Commun., 2014, 50, 14241 DOI: 10.1039/C4CC05976J

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