Highly regio- and stereoselective nitro-oxoamination of mono-substituted allenes†
Abstract
A highly regio- and stereoselective (up to 99/1) nitro-oxoamination reaction of mono-substituted allene occurs under mild conditions with readily available AgNO2 and a free radical trap TEMPO to form one C–N bond and one C–O bond in one step. Various functional groups and heterocycles could be tolerated in this conversion.