Issue 82, 2014
From the journal:

Chemical Communications

A highly selective and sensitive “turn-on” fluorescence chemodosimeter for the detection of mustard gas†

D. Raghavender Goud,a   Ajay Kumar Purohit,a   Vijay Tak,a   Devendra Kumar Dubey,a   Pravin Kumarb  and  Deepak Pardasani*a  

* Corresponding authors

a Vertox Laboratory, Defence Research and Development Establishment, Jhansi Road, Gwalior, M.P. 474002, India
E-mail: dkpardasani@drde.drdo.in
Fax: +0751-2341148

b Pharmacology & Toxicology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior, M.P. 474002, India

Abstract

A new chemodosimetric protocol based on a tandem S-alkylation followed by desulfurisation reaction of rhodamine-thioamide with mustard gas is reported. The chemodosimeter is highly selective for potential DNA alkylating agents like sulfur mustard, over other simple alkyl halides with the limit of detection of 4.75 μM.

Graphical abstract: A highly selective and sensitive “turn-on” fluorescence chemodosimeter for the detection of mustard gas

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC04801F
Article type
Communication
Submitted
24 Jun 2014
Accepted
21 Aug 2014
First published
21 Aug 2014

Chem. Commun., 2014,50, 12363-12366

Permissions

Request permissions

A highly selective and sensitive “turn-on” fluorescence chemodosimeter for the detection of mustard gas

D. Raghavender Goud, A. K. Purohit, V. Tak, D. K. Dubey, P. Kumar and D. Pardasani, Chem. Commun., 2014, 50, 12363 DOI: 10.1039/C4CC04801F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements