Issue 59, 2014

A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

Abstract

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0–5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations.

Graphical abstract: A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

Supplementary files

Article information

Article type
Communication
Submitted
29 Apr 2014
Accepted
03 Jun 2014
First published
13 Jun 2014

Chem. Commun., 2014,50, 8073-8076

Author version available

A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

O. El Bakouri, D. Cassú, M. Solà, T. Parella, A. Pla-Quintana and A. Roglans, Chem. Commun., 2014, 50, 8073 DOI: 10.1039/C4CC03190C

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