Jump to main content
Jump to site search

Issue 60, 2014
Previous Article Next Article

Covalent, sequence-specific attachment of long DNA molecules to a surface using DNA-templated click chemistry

Author affiliations

Abstract

We present a novel method that covalently and sequence-specifically attaches long DNA molecules to a surface that is compatible with high-resolution atomic force microscopy (AFM) imaging. Surfaces prepared with this approach are ideally suited for performing biophysical experiments on single DNA molecules.

Graphical abstract: Covalent, sequence-specific attachment of long DNA molecules to a surface using DNA-templated click chemistry

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Apr 2014, accepted on 04 Jun 2014 and first published on 06 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC02900C
Author version
available:
Download author version (PDF)
Citation: Chem. Commun., 2014,50, 8131-8133
  • Open access: Creative Commons BY license
  •   Request permissions

    Covalent, sequence-specific attachment of long DNA molecules to a surface using DNA-templated click chemistry

    G. R. Abel, B. H. Cao, J. E. Hein and T. Ye, Chem. Commun., 2014, 50, 8131
    DOI: 10.1039/C4CC02900C

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements