Quaternized carbon dot-modified graphene oxide for selective cell labelling – controlled nucleus and cytoplasm imaging

K. K. R. Datta; O. Kozák; V. Ranc; M. Havrdová; A. B. Bourlinos; K. Šafářová; K. Holá; K. Tománková; G. Zoppellaro; M. Otyepka; R. Zbořil

doi:10.1039/C4CC02637C

Quaternized carbon dot-modified graphene oxide for selective cell labelling – controlled nucleus and cytoplasm imaging†

K. K. R. Datta,^a O. Kozák,^a V. Ranc,^a M. Havrdová,^a A. B. Bourlinos,^a K. Šafářová,^a K. Holá,^a K. Tománková,^b G. Zoppellaro,^a M. Otyepka^a and R. Zbořil*^a

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^a Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Slechtitelu 11, 78371 Olomouc, Czech Republic
E-mail: radek.zboril@upol.cz

^b Department of Medical Biophysics, Faculty of Medicine and Dentistry, Institute of Translation Medicine, Palacky University in Olomouc, Hnevotinska 3, 775 15 Olomouc, Czech Republic

Abstract

Cationic quaternized carbon dots (QCDs) and anionic graphene oxide sheets (GO) are combined via non-covalent interactions following a self-assembly pathway to form highly biocompatible and fluorescent hybrid materials. These hybrids act as selective probes with controlled labelling of the cell nucleus or cytoplasm depending on the QCD loading.

Chemical Communications

Quaternized carbon dot-modified graphene oxide for selective cell labelling – controlled nucleus and cytoplasm imaging†

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Quaternized carbon dot-modified graphene oxide for selective cell labelling – controlled nucleus and cytoplasm imaging

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