Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose

Qiong Chen; Meiling Liu; Jiangna Zhao; Xue Peng; Xiaojiao Chen; Naxiu Mi; Bangda Yin; Haitao Li; Youyu Zhang; Shouzhuo Yao

doi:10.1039/C4CC01703J

Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose†

Qiong Chen,^a Meiling Liu,^a Jiangna Zhao,^a Xue Peng,^a Xiaojiao Chen,^a Naxiu Mi,^a Bangda Yin,^a Haitao Li,^a Youyu Zhang*^a and Shouzhuo Yao^a

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^a Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, P. R. China
E-mail: zhangyy@hunnu.edu.cn
Fax: +86 73188872531
Tel: +86 75188865515

Abstract

We demonstrate that photoluminescent Si-dots exhibit intrinsic peroxidase-like activity, and can catalyze the oxidization of 3,3′,5,5′-tetramethylbenzidine (TMB) by H₂O₂, and produce a color change. This strategy can be used to detect glucose with high sensitivity and selectivity.

Chemical Communications

Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose†

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Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose

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