Issue 37, 2014
From the journal:

Chemical Communications

Filamentous supramolecular peptide–drug conjugates as highly efficient drug delivery vehicles†

Miao Yang,‡a   Dawei Xu,‡a   Linhai Jiang,a   Lin Zhang,b   Derek Dustin,a   Reidar Lund,c   Ling Liub  and  He Dong*a  

* Corresponding authors

a Department of Chemistry and Biomolecular Sciences, Clarkson University, Potsdam, NY 13699, USA
E-mail: hdong@clarkson.edu

b Department of Mechanical and Aerospace Engineering, Utah State University, Logan, UT 84322, USA

c Department of Chemistry, University of Oslo, Postboks 1033 Blindern, 0315 Oslo, Norway

Abstract

We report here a facile approach to prepare filamentous supramolecular peptide–drug conjugates with precise drug/carrier stoichiometry, nearly 100% loading efficiency and exceptional anti-cancer drug efficacy for chemotherapy.

Graphical abstract: Filamentous supramolecular peptide–drug conjugates as highly efficient drug delivery vehicles

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Article information

DOI
https://doi.org/10.1039/C4CC01568A
Article type
Communication
Submitted
02 Mar 2014
Accepted
13 Mar 2014
First published
17 Mar 2014

Chem. Commun., 2014,50, 4827-4830

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Filamentous supramolecular peptide–drug conjugates as highly efficient drug delivery vehicles

M. Yang, D. Xu, L. Jiang, L. Zhang, D. Dustin, R. Lund, L. Liu and H. Dong, Chem. Commun., 2014, 50, 4827 DOI: 10.1039/C4CC01568A

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