Issue 52, 2014

Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

Abstract

A tailor-made colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids was developed by incorporating a coumarin–hemicyanine fluorophore into an isaindigotone framework. The significant and distinct changes in both the color and fluorescence of this probe enable the label-free and visual detection of G-quadruplex structures.

Graphical abstract: Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

Supplementary files

Article information

Article type
Communication
Submitted
26 Feb 2014
Accepted
01 May 2014
First published
07 May 2014

Chem. Commun., 2014,50, 6927-6930

Author version available

Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

J. Yan, S. Chen, H. Liu, W. Ye, T. Ou, J. Tan, D. Li, L. Gu and Z. Huang, Chem. Commun., 2014, 50, 6927 DOI: 10.1039/C4CC01472C

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