Water-soluble derivatives of pyrrolopyrrole cyanines (PPCys) have been synthesized by a post-synthetic modification route. In highly polar media, these dyes are excellent NIR fluorophores. Labeling experiments show how these novel dyes are internalized into mammalian cells.
S. Wiktorowski, C. Rosazza, M. J. Winterhalder, E. Daltrozzo and A. Zumbusch, Chem. Commun., 2014, 50, 4755 DOI: 10.1039/C4CC01014K
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