Issue 7, 2014
From the journal:

Chemical Communications

Fluorescence imaging lysosomal changes during cell division and apoptosis observed using Nile Blue based near-infrared emission†

Jiangli Fan,*a   Huijuan Dong,a   Mingming Hu,a   Jingyun Wang,b   Hua Zhang,a   Hao Zhu,a   Wen Suna  and  Xiaojun Peng*a  

* Corresponding authors

a State Key Laboratory of Fine Chemicals, Dalian University of Technology, No. 2 Linggong Road, High-tech District, Dalian 116024, China
E-mail: fanjl@dlut.edu.cn, pengxj@dlut.edu.cn
Fax: +86 411 84986306
Tel: +86 411 84986327

b Department School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China

Abstract

NBM, a Nile Blue based NIR fluorescent dye was reported. NBM is highly effective in specifically labeling lysosomes with low concentration and good photostability in various kinds of live cells. It was first successfully used to observe the disappearance and reproduction of lysosomes during cell division.

Graphical abstract: Fluorescence imaging lysosomal changes during cell division and apoptosis observed using Nile Blue based near-infrared emission

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Article information

DOI
https://doi.org/10.1039/C3CC48043G
Article type
Communication
Submitted
19 Oct 2013
Accepted
11 Nov 2013
First published
12 Nov 2013

Chem. Commun., 2014,50, 882-884

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Fluorescence imaging lysosomal changes during cell division and apoptosis observed using Nile Blue based near-infrared emission

J. Fan, H. Dong, M. Hu, J. Wang, H. Zhang, H. Zhu, W. Sun and X. Peng, Chem. Commun., 2014, 50, 882 DOI: 10.1039/C3CC48043G

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