Issue 14, 2014

Five-plex isotope dimethyl labeling for quantitative proteomics

Abstract

Stable isotope dimethyl labeling, a widely used method for quantitative proteomics, was extended to five channels for the first time. Comprehensive proteome and phosphoproteome quantification validated the high quantification accuracy and throughput of this five-plex method.

Graphical abstract: Five-plex isotope dimethyl labeling for quantitative proteomics

Supplementary files

Article information

Article type
Communication
Submitted
17 Oct 2013
Accepted
06 Dec 2013
First published
09 Dec 2013

Chem. Commun., 2014,50, 1708-1710

Five-plex isotope dimethyl labeling for quantitative proteomics

Y. Wu, F. Wang, Z. Liu, H. Qin, C. Song, J. Huang, Y. Bian, X. Wei, J. Dong and H. Zou, Chem. Commun., 2014, 50, 1708 DOI: 10.1039/C3CC47998F

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