Issue 5, 2014
From the journal:

Chemical Communications

High coating of Ru(ii) complexes on gold nanoparticles for single particle luminescence imaging in cells†

Nicola J. Rogers,‡a   Sunil Claire,‡b   Robert M. Harris,c   Shiva Farabi,a   Gerald Zikeli,a   Iain B. Styles,d   Nikolas J. Hodges*c  and  Zoe Pikramenou*a  

* Corresponding authors

a School of Chemistry, The University of Birmingham, Edgbaston, UK
E-mail: z.pikramenou@bham.ac.uk

b PSIBS Doctoral Training Centre, The University of Birmingham, Edgbaston, UK

c School of Biosciences, The University of Birmingham, Edgbaston, UK
E-mail: hodgesn@adf.bham.ac.uk

d School of Computer Sciences, The University of Birmingham, Edgbaston, UK

Abstract

Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.

Graphical abstract: High coating of Ru(ii) complexes on gold nanoparticles for single particle luminescence imaging in cells

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Article information

DOI
https://doi.org/10.1039/C3CC47606E
Article type
Communication
Submitted
04 Oct 2013
Accepted
05 Nov 2013
First published
05 Nov 2013

Chem. Commun., 2014,50, 617-619

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High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

N. J. Rogers, S. Claire, R. M. Harris, S. Farabi, G. Zikeli, I. B. Styles, N. J. Hodges and Z. Pikramenou, Chem. Commun., 2014, 50, 617 DOI: 10.1039/C3CC47606E

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