Application of a non-aqueous capillary electrophoresis method to the analysis of triclosan in personal care products

Abstract

A non-aqueous capillary electrophoresis (NACE) method was developed for analyzing triclosan in personal care products. The factors influencing the NACE analysis were investigated. The non-aqueous running buffer was 60 : 40 (v/v) methanol–acetonitrile containing 1 mmol L⁻¹ sodium tetraborate, with 9 s hydrodynamic injection, 25 kV applied voltage, and UV detection at 204 nm. The migration time of triclosan was about 4 min. Personal care product samples were extracted with methanol under ultrasonication for 20 min, with a linear range of 0.25–50 μg mL⁻¹ and a detection limit at 0.075 μg mL⁻¹. The proposed NACE method obtained a low detection limit and showed a satisfactory analytical performance.