Issue 23, 2014
From the journal:

Analyst

Visualization of monoamine oxidases in living cells using “Turn-ON” fluorescence resonance energy transfer probes†

Xuefeng Li,a   Jiajun Yu,a   Qing Zhu,*a   Linghui Qian,b   Lin Li,b   Yuguo Zheng*a  and  Shao Q. Yao*b  

* Corresponding authors

a Institute of Bioengineering, Zhejiang University of Technology, Chaowang Road 18, P. R. China 310014
E-mail: zhuq@zjut.edu.cn, ygzheng@zjut.edu.cn
Fax: +86 88320781
Tel: +86 88320781

b Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543
E-mail: chmyaosq@nus.edu.sg
Fax: +65 67791691
Tel: +65 65162925

Abstract

Novel FRET-based small molecule probes targeting monoamine oxidases (MAOs) were designed and synthesized. These “Turn-ON” fluorescent probes were proved to be capable of directly reporting MAO activities in live mammalian cells.

Graphical abstract: Visualization of monoamine oxidases in living cells using “Turn-ON” fluorescence resonance energy transfer probes

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C4AN01195C
Article type
Communication
Submitted
03 Jul 2014
Accepted
06 Sep 2014
First published
08 Sep 2014

Analyst, 2014,139, 6092-6095

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Visualization of monoamine oxidases in living cells using “Turn-ON” fluorescence resonance energy transfer probes

X. Li, J. Yu, Q. Zhu, L. Qian, L. Li, Y. Zheng and S. Q. Yao, Analyst, 2014, 139, 6092 DOI: 10.1039/C4AN01195C

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