Issue 7, 2014

Facile synthesis of water-soluble and biocompatible fluorescent nitrogen-doped carbon dots for cell imaging

Abstract

A simple, facile and green hydrothermal method was developed in the synthesis of water-soluble nitrogen-doped carbon dots (N-CDs) from streptomycin. The as-prepared N-CDs displayed bright blue fluorescence under the irradiation of UV light, together with a high quantum yield of 7.6% and good biocompatibility as demonstrated by the cell viability assay. Thus, the N-CDs can be used as fluorescent probes for cell imaging, which have potential applications in bioimaging and related fields. This strategy opens a new way for the preparation of fluorescent carbon nanomaterials using small molecules as carbon sources.

Graphical abstract: Facile synthesis of water-soluble and biocompatible fluorescent nitrogen-doped carbon dots for cell imaging

Supplementary files

Article information

Article type
Paper
Submitted
09 Nov 2013
Accepted
08 Jan 2014
First published
08 Jan 2014

Analyst, 2014,139, 1692-1696

Author version available

Facile synthesis of water-soluble and biocompatible fluorescent nitrogen-doped carbon dots for cell imaging

W. Wang, Y. Lu, H. Huang, J. Feng, J. Chen and A. Wang, Analyst, 2014, 139, 1692 DOI: 10.1039/C3AN02098C

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