Issue 34, 2013

Dendrimer-based nanodevices for targeted drug delivery applications

Abstract

This review reports some recent advances on the use of dendrimers as a versatile platform for targeted drug delivery applications. The unique 3-dimensional architectures and macromolecular characteristics afford dendrimers with ideal drug delivery ability through encapsulating drugs in their interior or covalently conjugating drugs on their surfaces. The adaptable surface functionalization ability enables covalent conjugation of various targeting molecules onto the surface of dendrimers, thereby allowing for generation of various multifunctional nanodevices for targeted drug delivery applications. In particular, the application of dendrimers as versatile platforms for targeted cancer therapeutics will be introduced in detail.

Graphical abstract: Dendrimer-based nanodevices for targeted drug delivery applications

Article information

Article type
Feature Article
Submitted
22 May 2013
Accepted
10 Jul 2013
First published
11 Jul 2013

J. Mater. Chem. B, 2013,1, 4199-4211

Dendrimer-based nanodevices for targeted drug delivery applications

J. Zhu and X. Shi, J. Mater. Chem. B, 2013, 1, 4199 DOI: 10.1039/C3TB20724B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements