Issue 27, 2013

Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer

Abstract

A P(UDMA-co-MPS) copolymer was surface-functionalized through the polycondensation activity of the enzyme silicatein. The resulting biosilica coating significantly enhanced mineralization of osteoblastic cells, thereby revealing its osteogenic potential. Consequently, the functionalized copolymer may be explored as an alternative to conventionally used acrylics in applications where stable bone–material interfaces are required.

Graphical abstract: Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer

Supplementary files

Article information

Article type
Communication
Submitted
08 Mar 2013
Accepted
23 May 2013
First published
24 May 2013

J. Mater. Chem. B, 2013,1, 3339-3343

Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer

M. Wiens, T. Niem, T. A. Elkhooly, R. Steffen, S. Neumann, U. Schloßmacher and W. E. G. Müller, J. Mater. Chem. B, 2013, 1, 3339 DOI: 10.1039/C3TB20325E

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