Strategy to introduce an hydroxyapatite–keratin nanocomposite into a fibrous membrane for bone tissue engineering†
Abstract
An hydroxyapatite (HA)–keratin nanocomposite was introduced into an electrospun poly(L-lactic acid) (PLLA) fibrous membrane with good electrospinnability. Biological in vitro cell culture demonstrated that the incorporation of HA–keratin into PLLA fibers led to significant bone formation compared to that of the pure electrospun PLLA membrane.