Issue 4, 2013

Graphene oxide based fluorescent nanocomposites for cellular imaging

Abstract

Carbon based 2-D material graphene oxide (GO) is a promising platform for preparing composites for biomedical applications because of its superior water solubility and low toxicity. Herein, we reported a convenient route to prepare fluorescent nanocomposites incorporating water-soluble GO sheets and Zn doped AgInS2 nanoparticles. According to the study, the photoluminescence of the Zn doped AgInS2 nanoparticles was well maintained after the hybridization using GO. No obvious emission shift was observed and the PL intensity was stable for over three months with negligible quenching. The PEGylated AIZS–GO nanocomposites could be readily up-taken by NIH/3T3 cells (mouse embryonic fibroblast cell line) while no distinct cytotoxicity was observed. The subsequent in vitro cellular imaging of NIH/3T3 cells proved that the as-prepared AIZS–GO–PEG nanocomposites were potential fluorescent probes for biomedical targeting and imaging.

Graphical abstract: Graphene oxide based fluorescent nanocomposites for cellular imaging

Supplementary files

Article information

Article type
Paper
Submitted
16 Sep 2012
Accepted
06 Nov 2012
First published
06 Nov 2012

J. Mater. Chem. B, 2013,1, 512-521

Graphene oxide based fluorescent nanocomposites for cellular imaging

Y. Sheng, X. Tang, E. Peng and J. Xue, J. Mater. Chem. B, 2013, 1, 512 DOI: 10.1039/C2TB00123C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements