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Issue 29, 2013
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Advancements and challenges of patterning biomolecules with sub-50 nm features

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Abstract

In recent years, the patterning of biomolecules with sub-50 nanometer resolution has enabled fundamental studies on cellular interactions with their environment and the development of densely packed biosensors. To further these efforts, the ability to precisely position multicomponent, single biomolecules and small clusters in various shapes and patterns has emerged as a major challenge. We highlight recent strategies to immobilize biomolecules with sub-50 nanometer resolution, emphasizing the advancements and challenges associated with each approach.

Graphical abstract: Advancements and challenges of patterning biomolecules with sub-50 nm features

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Publication details

The article was received on 14 Jan 2013, accepted on 08 Mar 2013 and first published on 22 Mar 2013


Article type: Highlight
DOI: 10.1039/C3SM00149K
Citation: Soft Matter, 2013,9, 6578-6586
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    Advancements and challenges of patterning biomolecules with sub-50 nm features

    H. Tran, K. L. Killops and L. M. Campos, Soft Matter, 2013, 9, 6578
    DOI: 10.1039/C3SM00149K

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