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Issue 10, 2013
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Luminescent oligonucleotide-based detection of enzymes involved with DNA repair

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Abstract

DNA repair processes are responsible for upholding the integrity and stability of genomic DNA. Consequently, the development of analytical assays to monitor enzymes involved with DNA repair pathways is of great interest in a variety of disciplines, including biochemistry, cell biology and biotechnology. In this perspective, we highlight examples of the development of luminescent assays for the detection of enzymes involved with DNA repair that have been reported in the last several years.

Graphical abstract: Luminescent oligonucleotide-based detection of enzymes involved with DNA repair

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Publication details

The article was received on 05 May 2013, accepted on 07 Jun 2013 and first published on 25 Jun 2013


Article type: Perspective
DOI: 10.1039/C3SC51228B
Citation: Chem. Sci., 2013,4, 3781-3795

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    Luminescent oligonucleotide-based detection of enzymes involved with DNA repair

    C. Leung, H. Zhong, H. He, L. Lu, D. S. Chan and D. Ma, Chem. Sci., 2013, 4, 3781
    DOI: 10.1039/C3SC51228B

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