Issue 27, 2013
From the journal:

RSC Advances

Iodine-catalyzed oxidative system for cyclization of primary alcohols with o-aminobenzamides to quinazolinones using DMSO as the oxidant in dimethyl carbonate†

Wenlei Ge,a   Xun Zhuab  and  Yunyang Wei*a  

* Corresponding authors

a School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China
E-mail: ywei@mail.njust.edu.cn
Fax: +86(25)84317078

b Department of Chemical Engineering, Yancheng Textile Vocational Technology College, Yancheng, P. R. China.

Abstract

The iodine catalyzed one-pot two-step oxidative system for cyclization of primary alcohols with o-aminobenzamides to quinazolinones using DMSO as the oxidant has been achieved, providing a convenient and efficient method for the synthesis of quinazolinones in good to excellent yields via in situ oxidation of primary alcohols to aldehydes. The reaction was carried out in the green solvent DMC, under atmospheric conditions. The procedure is suitable for aromatic or alkyl primary alcohols.

Graphical abstract: Iodine-catalyzed oxidative system for cyclization of primary alcohols with o-aminobenzamides to quinazolinones using DMSO as the oxidant in dimethyl carbonate

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3RA40872H
Article type
Paper
Submitted
20 Feb 2013
Accepted
19 Apr 2013
First published
19 Apr 2013

RSC Adv., 2013,3, 10817-10822

Permissions

Request permissions

Iodine-catalyzed oxidative system for cyclization of primary alcohols with o-aminobenzamides to quinazolinones using DMSO as the oxidant in dimethyl carbonate

W. Ge, X. Zhu and Y. Wei, RSC Adv., 2013, 3, 10817 DOI: 10.1039/C3RA40872H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements