Issue 45, 2013
From the journal:

RSC Advances

Microwave-assisted copper-catalyzed hydroxylation of aryl halides in water†

Fang Ke,a   Xiaole Chen,a   Zhengkai Li,b   Haifeng Xiangb  and  Xiangge Zhou*b  

* Corresponding authors

a College of Pharmacy, Fujian Medical University, Fuzhou 350004, China

b Institute of Homogeneous Catalysis, College of Chemistry, Sichuan University, Chengdu 610064, China
E-mail: zhouxiangge@scu.edu.cn
Fax: +86-28-85412026
Tel: +86-28-85412026

Abstract

A simple and efficient protocol for microwave-assisted copper-catalyzed hydroxylation of aryl halides is developed. A variety of phenols can be obtained in moderate to excellent yields of up to 95%. Its application is performed to synthesize 2,3-dihydroxy-1,4-naphthoquinone, which displays significant anti-proliferation effect.

Graphical abstract: Microwave-assisted copper-catalyzed hydroxylation of aryl halides in water

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3RA44613A
Article type
Communication
Submitted
05 Aug 2013
Accepted
16 Sep 2013
First published
24 Sep 2013

RSC Adv., 2013,3, 22837-22840

Permissions

Request permissions

Microwave-assisted copper-catalyzed hydroxylation of aryl halides in water

F. Ke, X. Chen, Z. Li, H. Xiang and X. Zhou, RSC Adv., 2013, 3, 22837 DOI: 10.1039/C3RA44613A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements