Jump to main content
Jump to site search

Issue 38, 2013
Previous Article Next Article

A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Author affiliations

Abstract

Promoted by KOH under ball milling, anilines were efficiently transformed into isothiocyanates (in presence of 5.0 equiv. CS2) or symmetrical thioureas (in presence of 1.0 equiv. CS2), without using any other harsh or toxic decomposition reagent. Some in situ generated isothiocyanates can directly “click” with other amines to afford unsymmetrical thioureas.

Graphical abstract: A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Jun 2013, accepted on 23 Jul 2013 and first published on 24 Jul 2013


Article type: Communication
DOI: 10.1039/C3RA43252A
RSC Adv., 2013,3, 16940-16944

  •   Request permissions

    A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

    Z. Zhang, H. Wu and Y. Tan, RSC Adv., 2013, 3, 16940
    DOI: 10.1039/C3RA43252A

Search articles by author

Spotlight

Advertisements