Issue 39, 2013
From the journal:

RSC Advances

A new strategy to prepare glutathione responsive silica nanoparticles†

Zhigang Xu,a   Kelin Zhang,a   Xiaoyan Liua  and  Haixia Zhang*a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
E-mail: zhanghx@lzu.edu.cn
Fax: +86 931 8912582
Tel: +86 931 8912510

Abstract

We have synthesized novel glutathione (GSH) responsive silica nanoparticles by introducing disulfide bonds into silica nanoparticles, which are highly uniform in size and show excellent blood compatibility. The subsequent degradation process under physiological conditions shows their promising potential for medical treatment and diagnosis.

Graphical abstract: A new strategy to prepare glutathione responsive silica nanoparticles

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Article information

DOI
https://doi.org/10.1039/C3RA43098G
Article type
Communication
Submitted
20 Jun 2013
Accepted
05 Aug 2013
First published
07 Aug 2013

RSC Adv., 2013,3, 17700-17702

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A new strategy to prepare glutathione responsive silica nanoparticles

Z. Xu, K. Zhang, X. Liu and H. Zhang, RSC Adv., 2013, 3, 17700 DOI: 10.1039/C3RA43098G

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