Multi-component continuous separation chip composed of micropillar arrays in a split-level spiral channel
Abstract
The separation and concentration of blood components or biological functional microparticles, have become indispensable in various biomedical and environmental applications. In this paper, a chip with two rows of micropillar arrays along a spiral-channel, in which plasma and various blood cells with different sizes can be separated or enriched simultaneously, has been achieved. The proposed method combines crossflow,