Issue 21, 2013

Lithium tert-butoxide mediated α-alkylation of ketones with primary alcohols under transition-metal-free conditions

Abstract

LiOtBu was found to efficiently promote the α-alkylation reaction of ketones with primary alcohols, without the addition of any transition metal catalyst.

Graphical abstract: Lithium tert-butoxide mediated α-alkylation of ketones with primary alcohols under transition-metal-free conditions

Supplementary files

Article information

Article type
Communication
Submitted
07 Dec 2012
Accepted
03 Apr 2013
First published
04 Apr 2013

RSC Adv., 2013,3, 7739-7742

Lithium tert-butoxide mediated α-alkylation of ketones with primary alcohols under transition-metal-free conditions

Y. Liang, X. Zhou, S. Tang, Y. Huang, Y. Feng and H. Xu, RSC Adv., 2013, 3, 7739 DOI: 10.1039/C3RA23221B

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