Issue 12, 2013
From the journal:

RSC Advances

A simple and efficient approach to 2-alkynylbenzofurans under mild copper(i)-catalyzed conditions†

Jianming Liu,a   Ningfei Zhang,a   Yuanyuan Yue,a   Dong Wang,b   Yuanli Zhang,a   Xin Zhanga  and  Kelei Zhuo*a  

* Corresponding authors

a Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry nd Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China
E-mail: klzhuo@263.net
Fax: (+86)-373-3326336

b Department of Bio-Health Technology, College of Biomedical Science, Kangwon National University, Chuncheon, Gangwon-Do, Korea

Abstract

The copper(I)-catalyzed synthetic method for the preparation of 2-alkynylbenzofurans from gem-dihaloolefins has been established using DABCO and TBAF·3H2O as a cocatalyst. This methodology relies on a simple reaction system and inexpensive Cu salts as catalysts. It is generally applicable to gem-dihaloolefins and phenylacetylenes.

Graphical abstract: A simple and efficient approach to 2-alkynylbenzofurans under mild copper(i)-catalyzed conditions

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Article information

DOI
https://doi.org/10.1039/C3RA00093A
Article type
Communication
Submitted
08 Jan 2013
Accepted
10 Jan 2013
First published
11 Jan 2013

RSC Adv., 2013,3, 3865-3868

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A simple and efficient approach to 2-alkynylbenzofurans under mild copper(I)-catalyzed conditions

J. Liu, N. Zhang, Y. Yue, D. Wang, Y. Zhang, X. Zhang and K. Zhuo, RSC Adv., 2013, 3, 3865 DOI: 10.1039/C3RA00093A

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